Ambulatory Holter monitoring has long been used to diagnose arrhythmias, typically recording ECG data for 24–48 hours. In contrast, mobile cardiac telemetry (MCT) patches enable real-time ECG monitoring for up to 30 days, allowing for longer-term analysis. This study compares the arrhythmia and ectopy diagnostic yield of a 30-day MCT patch with that of a 24-hour Holter monitor to evaluate differences in patient outcomes.

In this study, wide complex tachycardia (WCT) was defined as a heart rate of ≥100 bpm for at least three consecutive beats, using reference annotations to locate episodes in ECG recordings. The ZywieAI® algorithm applies signal processing to remove artifacts, identify key signal points, and detect ectopic beats. It then calculates features from these signals and uses an AI-based classifier to determine true WCT episodes. The algorithm’s performance was evaluated at both the episode level and the recording level.

Over a 30-day period, the ZywieAI algorithm analyzed ECG data from 3,596 patients and identified 78,910 potential arrhythmia events, which were later reviewed by cardiac technicians and physicians. A retrospective analysis evaluated whether 57,192 key arrhythmias could be detected using single-channel (Lead II) data, and compared diagnostic yield between 14-day and 30-day monitoring periods.

Ambulatory ECG devices help physicians monitor heart rhythm issues outside the hospital. Unlike Holter monitors, which record for 24–48 hours, Mobile Cardiac Telemetry and Event monitors can track heart activity for up to 30 days. This study compares outcomes between shorter monitoring periods (1–14 days) and longer monitoring periods (15–30 days).