Every Heartbeat. Every Moment.
The Next-Generation Remote Cardiac Monitoring Solution.
Designed for Providers.
Made for Patients.
Zywie empowers clinicians with high-fidelity, AI-driven insights for early, accurate detection while ensuring patients have a discreet, comfortable experience that fits seamlessly into their lives. By balancing clinical precision with human-centric design, we aim to improve heart health outcomes without ever missing a beat.

Powerful Data
Improving patient outcomes
Unmatched Care
Convenience & clinical relevance
Effortless Access
Quickly address abnormal rhythm

% of additional patients identified between days 15-30 of monitoring
With advanced rhythm analysis and near real-time visibility. Your heart doesn’t take a break—and neither do we. Zywie’s connected cardiac monitoring transforms every beat into actionable insight, enabling proactive care that adapts as patients’ needs evolve.
Technology that extends care beyond the clinic
At Zywie, we deliver a seamless mobile experience designed to guide patients through their monitoring journey, providing uninterrupted data, clear insights, and confidence in their care.
Symptom & Event Logging
Patients can easily log symptoms and activities, seamlessly pairing clinical events with ECG data to provide critical context for accurate interpretation.
Near Real-Time Data Access
Continuous data transmission allows Zywie to review patient data as it’s collected—often before the monitor is returned—supporting faster insight and clinical responsiveness.
24/7 Patient Support
Zywie’s concierge support team assists patients with onboarding, app setup, patch changes, and troubleshooting—driving compliance and reducing clinic burden.



Every heartbeat tells a story
Zywie provides the actionable insight that makes it clear.

Faster Insights.
Higher Diagnostic Yield. Better Cardiac Care.
Zywie delivers high-precision cardiac insights for providers and a comfortable, lifestyle-friendly experience for patients. Our mission is to bridge the gap between clinical excellence and daily life for faster, smarter heart care.

Jerry
Heart Arrhythmia Patient
The Zywie Nano was easy and pain-free, caused no inconvenience, and quickly gave my cardiologist the clarity needed to understand my symptoms.

Jeff
Heart Arrhythmia Patient
I managed AFib for years, but during cancer treatment it worsened. Continuous monitoring revealed hidden triggers, helping my doctors restore control, improving my quality of life.

Dr. Christopher L. Daniels
Archbold Cardiology Clinic
When industry partners like Zywie show up as true collaborators, committed to helping us care for patients, that’s when partnerships are most impactful and create meaningful, lasting value.

Christopher J. Newman
Chief Operating Officer
Zywie makes it easy to scale our cardiology reach and better serve our community, with a solution that’s simple to implement and grows seamlessly across clinics as we expand into new markets.

Jackson Finn
Heart Arrhythmia Patient
Patients can easily log symptoms and activities, seamlessly pairing clinical events with ECG data to provide critical context for accurate interpretation.
Trusted by providers. Valued by Patients
500K+
Patients served
1T+
Heartbeats
4.5M+
Unique Notifications
More Data.
More Actionable Findings.
CLINICAL ARTICLE
Efficacy of long-term monitoring on detecting critical cardiac arrhythmias
Ambulatory ECG devices help physicians monitor heart rhythm issues outside the hospital. Unlike Holter monitors, which record for 24–48 hours, Mobile Cardiac Telemetry and Event monitors can track heart activity for up to 30 days. This study compares outcomes between shorter monitoring periods (1–14 days) and longer monitoring periods (15–30 days).
CLINICAL ARTICLE
Enhancing Arrhythmia Diagnosis: A Comparison Between One and Three-Channel ECG Recordings
Over a 30-day period, the ZywieAI algorithm analyzed ECG data from 3,596 patients and identified 78,910 potential arrhythmia events, which were later reviewed by cardiac technicians and physicians. A retrospective analysis evaluated whether 57,192 key arrhythmias could be detected using single-channel (Lead II) data, and compared diagnostic yield between 14-day and 30-day monitoring periods.
CLINICAL ARTICLE
Robust Detection of Wide Complex Tachyarrhythmias using Mobile Cardiac Telemetry Monitors
In this study, wide complex tachycardia (WCT) was defined as a heart rate of ≥100 bpm for at least three consecutive beats, using reference annotations to locate episodes in ECG recordings. The ZywieAI® algorithm applies signal processing to remove artifacts, identify key signal points, and detect ectopic beats. It then calculates features from these signals and uses an AI-based classifier to determine true WCT episodes. The algorithm’s performance was evaluated at both the episode level and the recording level.
Frequently Asked Questions
Can I shower with a Zywie Patch?
Yes, Zywie patches can get wet. However, please avoid direct water contact from excessively hot showers for extended periods of time. Additionally, do not submerge any Zywie patch in water.
Can I work out while wearing the Zywie Patch?
You can engage in various exercises while wearing the Zywie Patch; however, please avoid activities that involve submerging the monitor, such as swimming or using hot tubs.
How do I return my Zywie sensor?
When your study is complete place all contents inside of the kit and ship it back to Zywie using the prepaid label inside of your kit. Please be sure to include and send back the phone, sensor, sensor case etc. Please only ship your kit back via the shipping service that is listed on your label and get a drop off receipt every time.
Should I change my patch adhesive everyday?
No, you only need to change the patch adhesive when the sensor requires charging. You can see the battery percentage of your patch sensor on the Zywie phone. A message reminding you to charge the patch sensor will display on the phone screen when the sensor battery gets low and requires charging.
Who can I contact if I have questions or need extra supplies?
If you have questions or need additional supplies, you can reach us by emailing customer.service@zywie.healthcare or by calling our Customer Support Team at 877.858.7200 ext. 3 for assistance.
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